What should be closely monitored when administering a biotherapy agent?

When administering a biotherapy agent, closely monitoring infusion reactions and vital signs is critical. Biotherapy agents can provoke immune responses, which may lead to reactions ranging from mild to severe. Common infusion-related reactions include fever, chills, rash, difficulty breathing, and hypotension. These reactions can occur at the start of infusion or after multiple doses, making vigilant monitoring essential throughout the process.

Monitoring vital signs such as heart rate, blood pressure, temperature, and oxygen saturation provides immediate feedback on the patient's response to treatment. If any adverse effects arise, prompt recognition and intervention can significantly improve patient safety and outcomes. It's essential for healthcare providers to remain alert and prepared to manage potential complications associated with biotherapy administration.

Other monitoring aspects mentioned in the other options, such as blood glucose levels, electrolyte levels, or heart and respiratory rates, while important in specific contexts, do not directly address the immediate and crucial concerns associated with the administration of biotherapy agents. Therefore, prioritizing monitoring for infusion reactions and vital signs is essential for patient safety during treatment.