Which chemotherapy drug is known to require special handling due to its toxic nature?

Cisplatin is known to require special handling due to its toxic nature. This drug is a platinum-based chemotherapy agent that can cause significant harm if not handled properly. It is important for healthcare professionals to use appropriate personal protective equipment (PPE) when preparing and administering cisplatin, as exposure can lead to adverse effects, including acute kidney injury and other toxicities. The toxicity of cisplatin highlights the need for strict adherence to safety protocols in handling and disposal to protect healthcare workers and prevent environmental contamination.

Each of the other drugs listed also has specific considerations regarding handling and safety. For example, cyclophosphamide can cause severe tissue damage and has risks related to toxicity and biohazardous waste. Doxorubicin is an anthracycline that can cause cardiotoxicity and requires careful handling, especially due to its potential to cause extravasation. Fluorouracil is also considered hazardous and requires safe handling practices. However, cisplatin is particularly noted for its nephrotoxicity and potential environmental impact, making its safety protocols crucial in clinical settings.